@article{JOVS34337,
author = {Koei Ikeda and Kosuke Fujino and Yoshiko Masuda and Makoto Suzuki},
title = {Surgical treatment of synchronous multiple lung adenocarcinomas: experiment of 171 cases},
journal = {Journal of Visualized Surgery},
volume = {6},
number = {0},
year = {2020},
keywords = {},
abstract = {Background: It is unclear how to treat synchronous multiple lung adenocarcinoma (SMLA) cases, which are increasing with the development of high-resolution computed tomography (HRCT).
Methods: Retrospective review of 171 cases of SMLA who underwent curative intent surgery between 2010 and 2018. Lung volume-preserving surgery, segmentectomy or wedge resection, is preferred for ground glass opacity nodules (GGN) within 2.0 cm. Clinical observation is allowed for pure GGN within 1.0 cm.
Results: The 5-year recurrence-free survival rate after surgery was 95.2%, and the overall survival rate was 93%. Prognosis was correlated with the degree of progression of the dominant tumor. Tumor number, surgical procedure and remnant tumor after surgery were not correlated with prognosis.
Conclusions: The prognosis of SMLA was relatively good, and was dependent on the stage and malignant potential of the dominant tumor. Limited resection and clinical observation for GGN are acceptable.},
issn = {2221-2965}, url = {https://jovs.amegroups.org/article/view/34337}
}