TY - JOUR AU - Hamaji, Masatsugu AU - Chen-Yoshikawa, Toyofumi-Fengshi AU - Matsuo, Yukinori AU - Motoyama, Hideki AU - Hijiya, Kyoko AU - Menju, Toshi AU - Aoyama, Akihiro AU - Sato, Toshihiko AU - Sonobe, Makoto AU - Date, Hiroshi PY - 2017 TI - Salvage video-assisted thoracoscopic lobectomy for isolated local relapse after stereotactic body radiotherapy for early stage non-small cell lung cancer: technical aspects and perioperative management JF - Journal of Visualized Surgery; Vol 3 (June 2017): Journal of Visualized Surgery Y2 - 2017 KW - N2 - Limited data is available on salvage surgery for local relapse (LR) after stereotactic body radiotherapy (SBRT) for non-small cell lung cancer (NSCLC). We aimed to characterize treatment options and clarify long-term outcomes of isolated LR after SBRT for patients with clinical stage I NSCLC. Herein, we discuss technical aspects, perioperative management, and postoperative follow-up of two patients of the 12 patients undergoing salvage surgery for LR after SBRT at Kyoto University between 1999 and 2013. A 76-year-old male, 15 months after SBRT, underwent a salvage right upper lobectomy combined with adjacent right lower lobe wedge resection via video-assisted thoracoscopic surgery (VATS) for a 5.0-cm mass. Local recurrence was found 5 years after salvage surgery and treated with repeat SBRT, however he died from multiple distant metastases. An 85-year-old male, 14 months after SBRT, underwent a salvage left upper lobectomy via VATS for a 3.5-cm mass. Moderate intrapleural adhesion was noted and required careful dissection on the mediastinum. He is alive with no recurrence at 2 years from salvage surgery. Salvage VATS lobectomy was feasible after SBRT in two patients. Long-term follow-up and continued discussions at multidisciplinary conferences are required. UR - https://jovs.amegroups.org/article/view/15368