%0 Journal Article %T Laparoscopic total pancreatectomy with islet autotransplantation for chronic pancreatitis %A Blair, Alex B. %A Burkhart, Richard A. %A Hirose, Kenzo %A Makary, Martin A. %J Journal of Visualized Surgery %D 2016 %B 2016 %9 %! Laparoscopic total pancreatectomy with islet autotransplantation for chronic pancreatitis %K %X Background: Pain from chronic pancreatitis can be debilitating and have far-reaching personal and societal consequences. These consequences can include patient debilitation, worsening of comorbid conditions, narcotic dependence, and implications for health care policy. A variety of surgical procedures have shown limited efficacy for relieving pain in this cohort of patients, and a highly select subset may benefit from a total pancreatectomy (TP). While a brittle form of diabetes can result from TP alone, when combined with islet cell autotransplantation this procedural complication can be minimized. Further, utilizing a minimally invasive approach may be associated with decreased periprocedural pain and length of hospital stay. Methods: We describe our experience at a single high-volume center in the United States. We present our preferred preoperative evaluation, our updated operative techniques, and the standard perioperative care required following this complex laparoscopic procedure. Results: Between 2013 and 2015, there were 20 patients who underwent laparoscopic total pancreatectomy with islet autotransplantation (LTPIAT). Perioperative mortality was 0%. Conclusions: At a high volume pancreatic center with experienced laparoscopic pancreatic surgeons, LTPIAT is feasible and safe for the management of chronic pancreatitis refractory to prior medical and surgical therapies. %U https://jovs.amegroups.org/article/view/11043 %V 2 %P %@ 2221-2965