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Laparoscopic total pancreatectomy with islet autotransplantation for chronic pancreatitis

	author = {Alex B. Blair and Richard A. Burkhart and Kenzo Hirose and Martin A. Makary},
	title = {Laparoscopic total pancreatectomy with islet autotransplantation for chronic pancreatitis},
	journal = {The Journal of Visualized Surgery},
	volume = {2},
	number = {7},
	year = {2016},
	keywords = {},
	abstract = {Background: Pain from chronic pancreatitis can be debilitating and have far-reaching personal and societal consequences. These consequences can include patient debilitation, worsening of comorbid conditions, narcotic dependence, and implications for health care policy. A variety of surgical procedures have shown limited efficacy for relieving pain in this cohort of patients, and a highly select subset may benefit from a total pancreatectomy (TP). While a brittle form of diabetes can result from TP alone, when combined with islet cell autotransplantation this procedural complication can be minimized. Further, utilizing a minimally invasive approach may be associated with decreased periprocedural pain and length of hospital stay. 
Methods: We describe our experience at a single high-volume center in the United States. We present our preferred preoperative evaluation, our updated operative techniques, and the standard perioperative care required following this complex laparoscopic procedure.
Results: Between 2013 and 2015, there were 20 patients who underwent laparoscopic total pancreatectomy with islet autotransplantation (LTPIAT). Perioperative mortality was 0%.
Conclusions: At a high volume pancreatic center with experienced laparoscopic pancreatic surgeons, LTPIAT is feasible and safe for the management of chronic pancreatitis refractory to prior medical and surgical therapies.},
	url = {}