Diagnostic imaging pathways in the setting of acute chest wall trauma
Review Article

Diagnostic imaging pathways in the setting of acute chest wall trauma

Carlos Galvez1, Juan Arenas-Jimenez2, Jone Del Campo1, Sergio Maroto1, Marina Sirera2, Francisco Lirio1

1Department of Thoracic Surgery, 2Department of Radiology, Hospital General Universitario Alicante, Alicante, Spain

Contributions: (I) Conception and design: C Galvez, J Arenas-Jimenez; (II) Administrative support: All authors; (III) Provision of study materials or patients: All authors; (IV) Collection and assembly of data: C Galvez, J Arenas-Jimenez; (V) Data analysis and interpretation: All authors; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors.

Correspondence to: Carlos Galvez, MD, PhD. C/Pintor Baeza, 12. 03010, Alicante, Spain. Email: carlos.galvez.cto@gmail.com.

Abstract: Recognition of thoracic injuries during trauma assessment must be a priority due to the potential severity of intrathoracic or intrabdominal lesions. While primary care is carried out following the Advanced Trauma Life Support (ATLS) protocols, special attention must be taken to detect life-threatening conditions such as tension pneumothorax, pericardial tamponade or massive hemothorax, guided by clinical suspicion, assessment of the trauma mechanism and noninvasive imaging techniques available in situ or in the emergency department. Chest X-ray and bedside ultrasound (focused assessment in sonography for trauma, FAST) are the initial tests for unstable patients, higher clinical suspicion or high-energy mechanism of accident. After initial resuscitation, during the secondary surgery, chest computed tomography (CT) is the cornerstone test for assessing the presence of intrathoracic lesions secondary to penetrating or high-energy trauma, that can potentially threaten patient’s life. Concise and early detection can be life-saving and determines the final results. In this article we review these techniques and their indications.

Keywords: Thoracic injuries; diagnostic imaging; Advanced Trauma Life Support Care (ATLS Care)


Received: 02 October 2019; Accepted: 04 November 2019; Published: 05 April 2020.

doi: 10.21037/jovs.2019.11.08


Introduction

Thoracic trauma is one of the most common locations of injury (after head and extremities), and has an overall mortality rate of up to 10% (1), so recognition of intrathoracic injuries must be a priority in chest trauma assessment. Trauma is the fifth leading cause of death worldwide, and is the leading cause in people younger than 40 years old (2).

Patients with chest wall trauma are at significant risk for intrathoracic or intraabdominal injuries based upon their mechanism of injury or initial clinical assessment, thus, unless they require immediate surgery, these patients usually warrant further diagnostic imaging.

Either for life threatening conditions that require an emergent response, or for minor injuries, imaging is a key tool to guide many of the interventions and decisions in patients with chest trauma. Conventional tests like chest radiographs and ultrasound, and computed tomography (CT) are the imaging techniques usually performed in the emergency setting (3).

We should review traumatic thoracic injuries from a severity point of view. Despite borders among the clinical outcomes of different lesions are not always clearly defined, and some initially irrelevant lesions can turn into clinical severe conditions, we can divide traumatic thoracic lesions into three levels of priority and severity, and imaging tests should be used accordingly: life-threatening conditions, injuries associated to high energy trauma, and mild chest trauma.

Portable chest X-ray (CXR) is usually the first imaging test to be performed in major trauma patients, since it can detect life-threatening injuries such as tension pneumothorax, massive hemothorax, and malposition of tubes or lines (4). Bedside thoracic ultrasound (focused assessment in sonography for trauma, FAST) in experienced hands can aid to quickly guide management of some of these events, which cannot await until CT is performed. For high-energy trauma, CT is mandatory, since it depicts the whole range of traumatic chest lesions together with abdominal, neurological and spine injuries that frequently concur in these patients. For mild chest trauma, conventional upright posteroanterior and lateral chest radiographs together with oblique views detect many chest wall and associated pleural lesions. In these patients, chest ultrasound is a reliable technique (5) that can even detect more rib fractures than radiographs.

In this review article, we will describe the indications of these diagnostic techniques, when to use each technique, their role and limitations, and the main imaging findings of most important traumatic lesions.


Primary survey: life-threatening conditions

First step in a thoracic trauma setting is to identify life-threatening conditions that might potentially lead to patient’s death. The classic management protocol from Advanced Trauma Life Support (ATLS) (3) from the American College of Surgeons is vital to initiate resuscitation while detecting some of these challenging conditions. Clinical signs and symptoms are cornerstone, but in many cases, prompt diagnosing tests are essential for making the correct management decisions.

These imaging tests should be easily and quickly available in the prehospital setting or in the Emergency Department (ED), should be reliable, and must not delay decision-making process. Plain CXR (either portable or conventional posteroanterior) and ultrasound are mainly the initial tests to rule out the potentially fatal injuries.

The aim of these tests is to early detect tension pneumothorax, massive hemothorax, pericardiac tamponade, airway rupture and flail chest.

CXR

CXR is useful during the primary survey of thoracic trauma, either in the ED or in the operating room (OR), in order to detect life-threatening injuries that may be missed. It is inexpensive, noninvasive, and easy to obtain.

It should be performed in any patient with concerning chest wall trauma, and can be avoided in superficial soft tissues injuries where intrathoracic injuries are unlikely. A normal CXR in low-risk patients avoids the need for further studies.

The NEXUS (National Emergency X-radiography Utilization Studies) Chest decision instrument showed that severe intrathoracic injury is highly unlikely in the absence of all the criteria shown in Table 1, so if one is present, an initial simple test like CXR should be performed (6).

Table 1
Table 1 NEXUS chest criteria
Full table

These criteria have proved high sensitivity (98.8%) and negative predictive value (98.5%) for detection of thoracic injury seen on chest imaging, but with low specificity (13.3%), which means that many positive results are false positives (7).

In cases of penetrating trauma, if a chest CT is planned, there is usually no need for a routine plain CXR, but it is recommended even in stable patients, because it can show subdiaphragmatic air, foreign bodies/fragments, pneumo- or hemothorax.

CXR is performed in blunt trauma of any significance, either if clinical findings suggest injury (Table 2) or in hemodynamically unstable patients, unless they require immediate chest CT or urgent surgery (8). In these high-risk patients, portable anteroposterior CXR might not have enough sensitivity to detect injury, so minor findings on CXR or clinical concern should be followed by advanced imaging tests like chest CT.

Table 2
Table 2 Clinical findings suggesting intrathoracic injury
Full table

CXR in blunt trauma can evidence the presence of pneumothorax, hemothorax, pulmonary contusion, bone fractures and signs of blunt aortic injury (BAI). In spite of its proven clinical utility, it must be kept in mind that many of the injuries found on CT (mainly multi-detector CT), are missed on CXR, and 20% of these lesions can influence decision-making (1).

Findings

Initial assessment with CXR aims to discover life-threatening conditions such as tension pneumothorax, massive hemothorax, pericardial tamponade, severe flail chest or airway rupture.

  • Tension pneumothorax: the “visceral pleura lineal sign” is the most common finding in traumatic pneumothorax, and reflects separation between both visceral and parietal pleural layers with air trapped inside (4). In absence of the characteristic pleural line, other radiological signs that help to diagnose pneumothorax in the supine position CXR are the “deep sulcus sign” finding a hyperlucent and deepened costophrenic sulcus, the “double diaphragm sign” due to basal air laying above the diaphragm, and a “unilateral hyperlucent lung” without an apparent visceral pleural line (4,9,10) (Figure 1).
  • If not detected in an early stage, pneumothorax can evolve into tensional, that is a clinical diagnosis that usually manifests radiologically as contralateral mediastinal shift, diaphragm inversion and widening of intercostal spaces. This is a life-threatening situation with risk of cardiac arrest and requires prompt pleural decompression with the available tools (3).

  • Massive hemothorax: accumulation of blood in the pleural space can be life-threatening if massive or can evolve into pleural complications like fibrothorax or clotting with subsequent empyema. Opacification of the lower hemithorax or the costophrenic sulcus is the most common radiological finding in CXR (Figure 2), with massive hemothorax appearing as whole opacification of the hemithorax (4), and potential diaphragmatic inversion or mediastinal shift (4,11). If concomitant with pneumothorax, an air-fluid level can be easily detected.
  • With the exception of small collections due to rib fractures, it’s recommended to drain with a large caliber chest tube (24–28 Fr) and if necessary fluid and/or blood infusion. Some cases of high initial output (>1,500 cc) with hemodynamic instability, persistent high output (>200 cc 2–4 hours) or need for repeated blood transfusion, claim for urgent surgical review (3).

  • Pericardial tamponade: although more common in penetrating trauma, injuries to the heart or pericardium may potentially produce cardiac tamponade due to accumulation of blood in the pericardial space, with the subsequent risk of cardiac arrest. Assessment of clinical signs such as arterial hypotension, paradoxical pulse and diminished heart sounds is of major importance, and CXR can give some suspicion signs.
  • Global enlargement of cardiac silhouette is the most common radiological finding (Figure 3). Other signs include the “water-bottle sign” and the “oreo cookie sign” (separation of epicardiac and pericardial fat by pericardial effusion) (1). Pneumopericardium or abnormal cardiac silhouette due to herniation of some part of the heart through pericardial tears are less frequent findings (4).

    Urgent subxiphoid or parasternal pericardiocentesis, followed by surgical exploration are the indicated therapeutic options (3).

  • Severe flail chest: flail chest is in fact a clinical diagnosis. Secondary to thoracic trauma, some ribs can break in two different locations, so when several ribs are affected, a segment of the chest wall exhibits paradoxical motion while breathing, collapsing during inspiration and protruding in expiration (1). When a significant segment of the chest wall is affected, patients can develop respiratory insufficiency, sometimes requiring orotracheal intubation and mechanical ventilation (12).
  • Evidence of three or more adjacent ribs broken in two different locations associated with clinical worsening should concern of a potential complication.

  • Airway rupture: although not considered traditionally a life-threatening condition in the primary survey, tracheobronchial rupture might become an emergency and, in fact, the majority of airway ruptures are fatal prior to arrive to hospital (1). They should be suspected after high-speed deceleration or crush injuries, which can compress the airway against bone structures, tear from fixed structures or elevate internal pressure against a closed glottis.
Figure 1 Tension pneumothorax. In chest X-ray, pneumothorax extends along the whole right hemithorax widening intercostal spaces, with a complete collapse of the right lung and displacing mediastinum to the left.
Figure 2 Massive hemothorax. (A) Chest X-ray shows right hemithorax opacification with left mediastinum displacement; (B) axial view in CT shows contralateral mediastinal displacement and ipsilateral lung compression. CT, computed tomography.
Figure 3 Pericardial tamponade. (A) chest X-ray shows significant enlargement of cardiac silhouette; (B) chest CT axial section shows blood in the pericardial space, mainly located in the lateral wall. CT, computed tomography.

Severe pneumomediastinum and/or subcutaneous emphysema, or persistent collapsed lung after chest tube placement in a pneumothorax are typical radiological signs, and must alert of the need for diagnostic and therapeutic fiberbronchoscopy and, in some cases, orotracheal intubation beyond the disrupted area (13) (Figure 4).

Figure 4 Airway rupture. (A) Chest X-ray showing subcutaneous emphysema at the neck base is readily apparent; mediastinal air in left is also seen; (B) traumatic pneumomediastinum without other significant lesions. Linear intrapulmonary air due to Macklin effect is shown in the right upper lobe (arrow). Subcutaneous and extrapleural air in the paravertebral and intercostal fat are also seen.

Focused assessment with sonography for trauma (FAST)

Identification of pathologic pericardial, intrathoracic or intraperitoneal free fluid as hypo or anechoic, or the presence of pneumothorax, are the main objectives of FAST (14,15). It is only contraindicated in patients who need immediate surgery.

Ultrasonography has the potential advantage of decreasing initial evaluation time and exposure to ionizing radiation, it is easy to learn, noninvasive and inexpensive, and can be easily repeated while the patient remains in the ED thus allowing for continuous reassessment of the patient increasing its accuracy (16).

FAST is performed in unstable patients (primary survey) and stable patients with chest wall trauma (secondary survey), for identifying life-threatening conditions, mainly cardiac tamponade and intraperitoneal bleeding, as well as massive hemothorax and pneumothorax (extended-FAST).

As FAST is not performed by skilled ultrasonographers, in the ED setting, it plays just an initial screening role in the management of thoracic trauma, and does not avoid the need for further studies in stable patients (chest CT), but it has the potential to diagnose intraperitoneal bleeding that directly leads to abdominal surgery in severely unstable patient.

Ultrasonography has limited and heterogeneous sensitivity (42–100%) (17), thus negative results in high-suspicion stable patients must carry the performance of further imaging tests or invasive maneuvers like pericardial window. It is more sensitive for injury in blunt trauma than in penetrating trauma, thus negative results in penetrating trauma must be taken with caution.

According to the guidelines of ATLS, the FAST exam is typically performed during the assessment of circulation and hemorrhage in the primary survey (3). A low frequency (2.5 to 5 MHz) curvilinear probe is used to allow for appropriate depth view.

Standard order of evaluation is as follows:

  • Pericardial (rule out pericardial tamponade first);
  • Right flank (hepatorenal view);
  • Left flank (perisplenic view);
  • Pelvic (retrovesical view);
  • Thoracic (rule out pneumothorax and hemothorax).

Some conditions can difficult ultrasound assessment by FAST, such as subcutaneous emphysema or hyperinflated lungs from chronic pulmonary disease.

Findings

  • Pericardial tamponade/hemopericardium: the first and main objective is to detect the presence of pericardial fluid (blood) between the two layers of pericardium, as an anechoic dark image. It can detect as little as 20 cc of fluid in the pericardial space (18) and also allows the operator to assess the presence of pericardial tamponade by evaluating wall motion or right ventricle filling abnormalities.
  • Epicardial fat pads can be distinguished because they move synchronous to heart wall motion, while pericardial bleeding remains independent (19). Most common window for cardiac review is the subcostal view, performed in the subxiphoid region. Alternatives are the parasternal long and the apical four chamber views. After an initial negative result in the setting of a high clinical suspicion, it’s recommended to repeat again the pericardial examination once the hemothorax has been removed with a chest tube. The reason is that a pericardial tear can drain blood from the pericardial space into the pleura, and also the presence of blood in the pleural space limits pericardial assessment (19,20).

    Ultrasonography has showed 100% and 96.9% sensitivity and specificity respectively for the diagnosis of hemopericardium, and mean time to surgery of 12.1 min in a prospective study with 261 cases of penetrating thoracic trauma, 29 of whom had findings of hemopericardium (21). It can also improve survival compared to non-ultrasonography use (22), and decrease the need for pericardial sub-xiphoid windows to assess the presence of hemopericardium (23).

  • Hemothorax: accumulation of blood in the pleural space appears as hypoechoic stripe in the FAST examination (as little as 20 cc is potentially visualized) (24,25), and it is usually located in the posterior costophrenic sulcus in the supine patient. It should alert on the possibility of intrathoracic injury and many times requires further imaging tests or procedures such as chest tube placement. Right and left flank views are typically used to rule out hemothorax. Ultrasonography has been shown to be more sensitive and specific for traumatic hemothorax when compared to CXR with nearly a 100% sensitivity and specificity for hemothorax, and almost none false positives in skilled operators (25,26).
  • Pneumothorax: pneumothorax is one of the most common serious injuries in the thorax, and one of the most frequent preventable causes of death in trauma, thus the importance of early diagnosis (16). The presence of air in the pleural space requires detailed visualization of the interface between both layers, with a high-frequency (5–10 MHz) linear transducer probe. The third-fourth intercostal space midclavicular line is the most typical location for this purpose, but there is no determined best approach. Common findings for pneumothorax are lack of sliding of the pleural layers (Figure 5) and lack of the comet tail sign (areas of interstitial edema in the visceral pleura). Presence of pleural sliding adjacent to areas of absence of this sign usually represent the edge of a pneumothorax. In cases of tension pneumothorax, no pleural sliding can be visualized in the affected hemithorax.
Figure 5 The lack of pleural sliding between both the parietal and visceral layers in a patient with traumatic pneumothorax (27). Available online: http://www.asvide.com/watch/33075

Multiple studies suggest ultrasonography is more sensitive than supine CXR for diagnosing pneumothorax (28-31), using chest CT as the gold standard. A 2012 meta-analysis showed a 90.9% sensitivity, 98.2% specificity, and 94.4% and 97% of positive and negative predictive values respectively (32).

What is not still determined is the need for further treatment in cases of small pneumothoraces found during e-FAST examination, as it happens in chest CT (16).


Secondary survey: high-energy trauma

Once life-threatening injuries have been discarded and the patient is stabilized, most patients with high-energy trauma are evaluated with CT. CT is the technique of choice since it can confidently detect and depict most traumatic lesions and permits an integrated evaluation of accompanying abdominal and skeletal lesions.

Although for a review purpose an anatomical division of the possible injuries is usually followed, lesions in multiple anatomical spaces are more frequent, and due to the unique characteristic of the lung as an air-filled viscus, for each anatomic location air and fluid/hematic collections of variable importance can be found.

It is not well determined yet if routine thoracoabdominal CT or if only selective CT should be performed in blunt high-energy trauma (2).

Chest wall

Depending on whether it has been a penetrating injury or not, and on the mechanism of trauma, lesions of the chest wall are varied.

Some grade of air collections is frequent in the chest wall fat, usually around muscular structures however, massive subcutaneous emphysema requiring direct intervention is rare. For blunt chest trauma, the presence of subcutaneous air should prompt further diagnostic search for pleural or mediastinal air as the origin.

Chest wall hematomas are almost always associated to rib fractures, and usually small or middle sized. When big, they are usually associated to anticoagulation or a vessel injury, mostly the intercostal arteries. In those cases, careful evaluation by means of CT angiography and if necessary delayed images to demonstrate active bleeding can help the interventional radiologist to guide an embolization (33). A specific type of chest wall hematoma is extrapleural hematoma that occurs when blood proceeding from the chest wall extends inside the thoracic cavity but does not traverse the intact parietal pleura. Extrapleural hematomas are limited by the endothoracic fascia, and characterized by the inward displacement of the extrapleural fat stripe (Figure 6). They are frequently associated to rib fractures and when show a biconvex shape, usually require surgical drainage (34).

Figure 6 Extrapleural hematoma. High attenuation collections in the extrapleural space are separated from the pleural effusion by a fat attenuation stripe. In (A) active bleeding from an intercostal artery is seen (arrow); in (B) the chest tube is inserted in the extrapleural space.

Rib fractures are a marker of severity in chest trauma, although their presence depends on the mechanism, strength and previous condition of the bone. Pain and potential flail chest are the main clinical consequences of rib fractures. Rib fracture fragments can transform blunt trauma into penetrating trauma (1) (Figure 7). In a large series (35) there was a significant association between the mortality rate and number of rib fractures, the patient’s age and injury severity score, and the number of rib fractures was significantly related with the presence of hemothorax or pneumothorax.

Figure 7 Rib fractures. (A) A severe thoracic trauma with multiple ribs broken in the right side producing a thoracoplasty with remodeling of chest wall shape; (B) axial CT with multiple ribs broken and some of them have torn the underlying lung parenchyma. CT, computed tomography.

Even with dedicated projections, radiography can miss rib fractures and both the use of sonography and CT detect more fractures (Figure 8). CT is the preferred diagnostic imaging test for rib fractures, and it can evidence mainly two types: buckling of the cortex (which are often missed in conventional CXR) and actual fracture gap (Figure 7B). However, missed rib fractures are not uncommon, specially buckle fractures, which are frequently overlooked (37). Dedicated software that permits unfolded reconstructions of the rib can aid to detect fractures in polytraumatized patients in a shorter time (38). Although it isn’t better for detecting fractures (39), 3D evaluation can better depict relationship of fracture fragments and guide surgical management if necessary. Recently, application of preoperative 3D printing before surgical stabilization has been shown to be useful for shortening operation time and to get a smaller incision length (40), although its use is not yet still well defined. Rib fracture evaluation should include the injured levels, number, alignment, inward displacement and the presence of segmental fractures with at least two separate complete fractures in the same rib, since all these factors can be associated to an increased risk of complications and consequently require a more aggressive management (41).

Figure 8 An extended FAST examination that diagnoses the presence of rib fracture (36). FAST, focused assessment in sonography for trauma. Available online: http://www.asvide.com/watch/33076

The upper ribs fractures (usually the first through third/fourth ribs) require high-energy trauma and may be associated with vascular or brachial plexus injury (9,10,42). First rib fractures are a marker of life-threatening injuries in major trauma, although in a study they do not independently increase mortality (42). Fractures below the eighth rib are significantly associated to intra-abdominal injury (43).

Sternal fractures are usually indicative of high-energy mechanism, mainly in traffic accidents, and almost all cases are associated with some grade of anterior mediastinal hematoma. Blunt cardiac injuries, specially right ventricle, should be ruled out and are more frequent in displaced fractures (44), with cervical spine injuries, multiple chest rib fractures and pulmonary contusions being frequent concomitant lesions (45). Location of the fracture in the manubrium is also an indicator of severity (46). Lateral projection CXR but especially multiplanar reconstructions on CT are essential for diagnosis (1) (Figure 9).

Figure 9 Displaced fracture of the body of the sternum accompanied by a small hematoma. (A) Lateral sternal radiography; (B) sagittal view in CT; (C) axial view in CT with underlying mediastinal hematoma (arrow). CT, computed tomography.

Scapular fractures are injuries associated to very high-energy mechanism usually appearing inferior to glenoid, and from lateral to medial. They can be easily missed in conventional CXR, and are commonly associated with other thoracic or upper extremities injuries. CT with three-dimensional reconstructions is valuable for diagnosis and planning treatment (1,10).

Pleural injuries

Hemothorax, pneumothorax or combined lesions are frequent in significant chest trauma. There have already been described the life-threatening conditions, but less important collections can be found associated to either parenchymal, mediastinal or chest wall injuries, in most instances with rib fractures.

Relative large amounts of either blood or air can be missed by decubitus chest radiographies. In a series, 55% of pneumothoraces diagnosed on thoracic CT were missed by conventional supine radiographies, with subcutaneous emphysema, pulmonary contusion, rib fractures, and female sex as independent predictors of these occult pneumothoraces (47).

Findings suggesting pneumothorax on supine radiographs have already been mentioned above and are an increased lucency of the lung base, the “double diaphragm”, excessive definition of mediastinal contour and perhaps the most reproducible “deep sulcus” sign (Figure 10). CT can also aid in the identification of the mechanism of the pneumothorax: an “outside-inside mechanism”, where rib fracture fragments tear parietal pleura, or the “inside-outside mechanism” where a sudden increase in the intrathoracic pressure can produce alveolar rupture (1).

Figure 10 Portable decubitus chest X-ray shows the “deep sulcus sign” pointing to a big sized pneumothorax.

CT measurement of Hounsfield units (HU) may distinguish between conventional pleural fluid (less than 15 HU) or probable blood that usually has an attenuation of 35–70 HU, reaching higher levels when clotting appears (1,9) (Figure 2B).

Apart from delimiting their cause, CT usually aids in the quantification and distribution of the collections and guides in their management. It must be kept in mind that mediastinal and abdominal lesions can be the origin of a pleural hematic collection. In large hemothorax, CT angiography can occasionally detect both the presence of active bleeding and the source, to potentially guide the interventional radiologist for embolization or the surgeon to proceed into an operation.

Pulmonary injuries

Pulmonary injuries can be mainly divided into those with alveolar disruption (laceration) or not (contusion) (1).

Pulmonary contusion is the most frequent lung damage after thoracic trauma, specially in blunt trauma. CT evidences pulmonary contusion at an early stage, as patchy airspace consolidation which do not follow pulmonary segmentation, and can be focal or multifocal, uni- or bilateral, or even diffuse (Figure 11).

Figure 11 Pulmonary contusion. (A) Chest X-ray shows consolidation in the right upper lobe; (B) axial CT shows consolidation in the right upper lobe together with several displaced rib fractures, right pneumothorax, pneumomediastinum and subcutaneous emphysema. CT, computed tomography.

Pulmonary lacerations are seen in penetrating trauma and high-energy blunt trauma, and usually coexist with contusion. They produce traumatic cavities in the lung (pneumatoceles, hematoceles or hemopneumatoceles) secondary to elastic recoil of lung tissue (Figure 12). They take weeks to months to completely recover and radiologically disappear, and if they affect the visceral pleura, a secondary traumatic pneumothorax can be seen. The most typical radiological appearance is a cavity filled with air and blood, but it can show only one of them. They can be classified into four types according to Wagner et al. (48):

  • Type 1: compression rupture of central areas secondary to sudden and acute compression of the lung, occurring specially in young patients with flexible thorax;
  • Type 2: compression shear, usually of the lower lobes resulting in a shearing injury across the spine, in the paravertebral areas;
  • Type 3: rib penetration with laceration secondary to fractured rib which tears the lung surface, usually associated with variable size of ipsilateral pneumothorax;
  • Type 4: adhesion tears secondary to previous pleuropulmonary adhesions; difficult to diagnose, require review of past history and imaging.
Figure 12 Pulmonary laceration. Consolidation and ground-glass opacities surround air cystic lesions corresponding to the lacerated lung. Arrow indicates pulmonary contusion.

Airway

Airway injuries are frequently seen after high-deceleration or crushing mechanisms of trauma, and usually become fatal before arriving to hospital. Disruption of airway wall is secondary to compression against bone, sudden elevation of intraluminal pressure against closed glottis, or shear in fixation points (9). These lesions are more common in the bronchi, within the 2 first centimeters from carina, and can be transverse or longitudinal.

CT can identify the exact disruption of the wall (between cartilages or in the junction between cartilage and membranous wall). An indirect sign of bronchial disruption is the “fallen lung” sign, where a lung remains collapsed in the lower portion of the cavity even though a chest tube has been inserted (4,10) (Figure 13).

Figure 13 Airway rupture. (A) Persistent pneumothorax after chest tube drainage, collapsed lung and big sized subcutaneous emphysema in plain chest X-ray; (B) left main bronchus is disrupted showing irregularities (arrow) in its wall and lumen in axial CT; (C) tracheal rupture showed by absence of the trachea in this axial section of the CT due to a complete transection with distraction of its borders. CT, computed tomography.

Although pneumomediastinum can occur in blunt trauma due to tracheobronchial and esophageal injuries, air usually originate from lung parenchymal injury. If the cause is not readily apparent, in a proportion of patients it is attributed to the Macklin effect that causes alveolar ruptures and air dissection along bronchovascular bundles. It is visualized as streaks of air surrounding and paralleling the bronchovascular bundles associated with pneumomediastinum (49) (Figure 4B).

Esophagus

Thoracic esophagus is rarely affected by thoracic trauma, because its central location and protection by surrounding structures (9). High-level falls are the main mechanism, and it’s difficult to exactly locate the esophageal site on injury, and common indirect signs visualized are hydropneumothorax or pneumomediastinum.

Heart and pericardium

Heart injuries can be fatal if severe, but low-degree of severity lesions can often be seen. Typical mechanisms of cardiac injury are direct impact, rapid deceleration or compression between the sternum and the spine. The preferred term for traumatic cardiac lesions is blunt cardiac injury that encompass all the spectrum of lesions. In patients at risk, a combination of electrocardiogram, troponin, and echocardiography is mandatory for an adequate diagnosis, risk stratification and management (50).

Hemopericardium and pulmonary edema are the most typical findings in CT (1) (Figure 3B). Direct extravasation of contrast to pericardium or mediastinum can sometimes be seen if chamber perforation.

Pericardium can also be damaged in blunt or penetrating trauma, and usually appears as hemo- or pneumopericardium. Partial heart herniation through pericardial defects can be seen in CT.

Diaphragm

Traumatic injuries of the diaphragm occur after penetrating (gunshot, stab wounds) but especially after blunt trauma (51) (deceleration, high-falls, crushing in the thoracoabdominal region), and many times remain undiagnosed for an indeterminate period, so its real incidence can be higher. Left side lesions are more commonly seen, probably secondary to the protecting effect of the liver in the right side (52,53).

In acute setting, consequences are directly related to associated injuries. In misdiagnosed cases, the pressure gradient between the abdomen and the thorax makes the diaphragmatic hernia increase in size during time, and a progressive herniation of abdominal organs into the thorax occurs (54). Acute, latent and obstructive are the common phases described by Grimes (55), with up to 85% of cases strangulated within 3 years of the original trauma (56).

Initial diagnostic test is CXR, where typical radiological findings (irregularity of diaphragmatic shape, elevation, mediastinal shift without other causes, and lower lobes atelectasis) in combination to clinical suspicion can be diagnostic enough. CT is the second-choice imaging test, with sensitivity and specificity up to 54–73% and 86–90% respectively (51,57,58) with state of the art multidetector CT scans being superior to conventional CT (57) due to their multiplanar reformation capabilities. Its main limitations are when thick slices are used (8–10 mm), limitations for delineating the diaphragm from adjacent soft-tissues due to small amount of fat that permits its visualization and respiratory motion (57,58) (Figure 14). CT can directly show the diaphragmatic defect itself, or indirectly show its existence as a stricture around the herniated viscus (the “collar or necklace sign”) or by demonstrating a direct contact of the herniated viscera and the posterior chest wall (the “dependent viscera sign”).

Figure 14 Traumatic diaphragmatic rupture. (A) Chest X-ray shows elevation of the right diaphragm with a hump corresponding to the herniated liver; (B) in the same patient as (A), CT performed 1 day later shows the liver in the right hemithorax; (C,D) axial and sagittal reformation in the same patient show a diaphragmatic defect [arrows in (D)] through which liver, mesentery fat and small bowel herniate. In both images the “dependent viscera sign” is seen with the viscera reaching the posterior pleural surface without the normal intervening diaphragm. In (D) the “collar sign” with a waist-like compression of the herniated structures at the level diaphragm defect (arrows) is seen. CT, computed tomography.

Aortic blunt injury

Traumatic aortic injury due to blunt chest trauma usually occurs as the result of motor vehicle collisions (59) and is an important cause of death at the accident scene. Aortic injury ranges from minimal intimal injury to complete aortic wall disruption and blood extravasation. The most common site of injury is the isthmus.

It should be suspected whenever a mediastinal hematoma next to the aorta is found on CT. An adequate thoracic CT angiography in a multidetector CT is the technique of choice for diagnosis, since it permits an adequate evaluation of the aortic lumen and the periaortic tissues.

It is beyond of the scope of this review the discussion on the management of traumatic aortic injuries, but it is clear that the diagnosis of minimal and contained ruptures is increasing due to the advances of imaging techniques (60) and that conservative and endovascular management are being recommended over the surgery in most instances (61,62).


Mild chest trauma

Soft tissue trauma and rib fractures are the most frequent lesions associated to mild chest traumas, that are frequently due to falls, mainly in the elderly population (63). As aforementioned, despite mild trauma is usually uncomplicated, it can be a threatening condition in older patients with comorbidities, since in that population rib fractures are associated to an increased mortality due to pulmonary complications (63,64).

Low-risk stable patients can be ordered conventional posteroanterior and lateral CXR, and if they don’t show any relevant findings, further tests can be avoided. Oblique views can help to detect more fractures, and dedicated ultrasound can detect even more rib fractures than radiographic techniques (65) but although they can give more details, they usually don’t alter therapeutic management.

It must be kept in mind that even in mild trauma, pneumothorax and hemothorax can occur, that lower ribs fractures can be associated to significant abdominal lesions (66) and that the number of fractures increases the risk of complication (35). Patients under anticoagulation therapy should be managed with caution for the risk of clinically important hemorrhagic complications.

Other bone lesions such as sternal fractures can occur in mild direct trauma, specially in old patients and, if isolated, it carries a good prognosis (67,68).

Sometimes mild traumas and persistent cough in emphysematous patients with weakened chest wall muscles present with pulmonary herniation through intercostal muscles. It can appear in combination to rib fractures, but might also appear isolated as a consequence of intercostal muscles disruption (Figure 15). These herniations are commonly undiagnosed initially, increase in size with time and the patients are referred for chest wall lumps with cough. CXR shows herniation of lung parenchyma through the intercostal space, and CT gives more detailed information about the exact site and size (69).

Figure 15 Traumatic pulmonary hernia developing after blunt chest trauma. Lung herniation though the intercostal space and a fractures callus are seen both in the chest X-ray and CT. (A) Posteroanterior chest X-ray with left pulmonary herniation (arrow); (B) axial view in CT of pulmonary herniation through intercostal disrupture (arrow). CT, computed tomography.

Conclusions

Thoracic trauma is a severe disease that must be addressed within trauma protocols, where clinical suspicion is essential for early diagnosis of potentially fatal injuries. Imaging tests are useful and reliable for classifying injuries in life-threatening conditions, injuries associated to high energy trauma and mild chest trauma. CXR and bedside ultrasound (FAST and e-FAST exams) are available, quick and non-invasive tests for early diagnosing life-threatening conditions such as tension pneumothorax, massive hemothorax or pericardial tamponade that claim for urgent actions or immediate surgery. Chest CT scan is mandatory in high-energy trauma where intrathoracic or intrabdominal secondary lesions can be expected. It also gives additional information for late management of injuries. Concise and prompt performance of these tests can be life-saving and determines the final outcomes. Flowchart (Figure 16) summarizes the different imaging tests and their indications.

Figure 16 Diagnostic management of thoracic trauma. ATLS, Advanced Trauma Life Support; NEXUS, National Emergency X-radiography Utilization Studies; CXR, chest X-ray; CT, computed tomography; FAST, focused assessment in sonography for trauma.

Acknowledgments

To all the patients that could not be saved, those where something better could be done, those who shed the light for improvement changes.


Footnote

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.


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doi: 10.21037/jovs.2019.11.08
Cite this article as: Galvez C, Arenas-Jimenez J, Del Campo J, Maroto S, Sirera M, Lirio F. Diagnostic imaging pathways in the setting of acute chest wall trauma. J Vis Surg 2020;6:21.